Some selected publications (some with links):

 

1.       S.C. Connolly, P.G. Smith, C. A Lall, D. J. Cole, G.N. Maksym. “Chronic mechanical strain increases the rate of stiffness recovery from acute stretch in airway smooth muscle cells”, Am J Physiol Lung Cell Mol. Physiol- in revision.

2.       C.A. Lall, N. Cheng, P. Hernandez, P.T. Pianosi, Z. Dali, A. Abouzied, and G.N. Maksym, "Airway resistance variability and response to bronchodilator in children with asthma" Eur Respir J Published on-line March 1, 2007, 10.1183/09031936.00064006

3.       An SS, Bai TR, Bates JHT, Black JL, Brown RH, Brusasco V, Chitano P, Deng L, Dowell M, Eidelman DH, Fabry B, Fairbank NJ, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gosens R, Gunst SJ, Halayko AJ, Ingram RH, Irvin CG, James AL, Janssen LJ, King GG, Knight DA, Lauzon AM, Lakser OJ, Ludwig MS, Lutchen KR, Maksym GN, Martin JG, Mauad T, McParland BE, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Paré PD, Pellegrino R, Sanderson MJ, Schellenberg RR, Seow CY, Silveira PSP, Smith PG, Solway J,  Stephens NL, Sterk PJ, Stewart AG, Tang DD, Tepper RS, Tran T, Wang L.   “Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma” Eur. Resp. J. in Press, 2007

4.       U. Frey, G.N. Maksym, M. Silverman, and B. Suki. New approaches to the understanding of complex chronic lung diseases. Eur Respir Monograph, 2006, 37, 345–360

5.       G.N. Maksym, L. Deng, N.J. Fairbank and S.C. Connolly. Beneficial and harmful effects of oscillatory mechanical strain on airway smooth muscle.  Can. J. Physiol & Pharm., 83(10):913-922, 2005.
- Invited and peer reviewed article for special edition on models of airway smooth muscle contraction.

6.       L. Matheson, N.J. Fairbank, G.N. Maksym, R. S. Labow. Characterization of the Flexcellä uniaxial strain system with U937 macrophage-like cells. Biomaterials. 2006 Jan;27(2):226-33.

7.       L. Deng, N.J. Fairbank, D.J. Cole, J.J. Fredberg and G.N. Maksym. Airway smooth muscle tone modulates mechanically induced cytoskeletal stiffening and remodeling  J. Appl. Physiol. 99:634-641, 2005, published on-line ahead of print (April 21, 2005).

8.       L. Matheson, G.N. Maksym, J. P. Santerre, R. S. Labow. Cyclic biaxial strain affects U937 macrophage-like morphology and enzymatic activities. J. Biomedical Materials Research: Part A. In press.

9.       TR Bai,  JH Bates, V Brusasco, B Camoretti-Mercado, P Chitano, Deng LH, M Dowell, B Fabry, LE Ford, JJ Fredberg, WT Gerthoffer, SH Gilbert, SJ Gunst, CM Hai, AJ Halayko, SJ Hirst, AL James, LJ Janssen, KA Jones, GG King, OJ Lakser, RK Lambert, AM Lauzon, KL Lutchen, GN Maksym, RA Meiss, SM Mijailovich, HW Mitchell, RW Mitchell, W Mitzner, TM Murphy, PD Paré, RR Schellenberg, CY Seow, GC Sieck, PG Smith, AV Smolensky, J Solway, NL Stephens, AG Stewart, DD Tang, and L Wang. On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol. 2004 Dec; 97(6):2029-34.

10.    X. Trepat, M. Grabulosa. F. Puig, G.N. Maksym, D. Navajas, and R. Farré. Viscoelasticity of human alveolar epithelial cells subjected to stretch, Am J Physiol Lung Cell Mol. Physiol 287(5):L1025-34. Nov 2004; Epub 2004 Jul 09.

11.    L. Deng, N.J. Fairbank, B. Fabry, P.G. Smith, and G.N. Maksym. Localized mechanical stress induces time-dependent actin cytoskeletal remodeling and stiffening in cultured airway smooth muscle cells. Am J Physiol Cell Physiol; 287: C440 - 448. Aug 2004

12.    P.G. Smith, L.Deng. J.J. Fredberg, G.N. Maksym. Mechanical strain increases cell stiffness through cytoskeletal filament reorganization. Am. J. Physiol: Lung Cell.Mol. Biol. 285:L456-L463, 2003.

13.    B. Fabry, G.N. Maksym, J.P. Butler, M. Glogauer, D. Navajas, N.A. Taback, E.J. Millet, J.J. Fredberg. Time scale and other invariants of integrative mechanical behavior in living cells. Physical Review E 68, 041914 , 2003
- this was selected for the November 1, 2003 issue of Virtual Journal of Biological Physics Research, http://www.vjbio.org. (Physical Studies of Cell Mechanics Section).

14.    1. P.G.Smith, L.Deng. J.J. Fredberg, G.N. Maksym. Mechanical strain increases cell stiffness through cytoskeletal filament reorganization. Am. J. Physiol: Lung Cell.Mol. Biol. 285:L456-L463, 2003.

15.    B. Fabry, G.N. Maksym, J.P. Butler, M. Glogauer, D. Navajas, J.J. Fredberg. Scaling of the microrheology of living cells. Physical Review Letters, 87:148102, 2001.
    This paper has been highlighted in:
        Nature Rev Mol Cell Biol vol 2:789, 2001 Soft Cells
        Physical Review Focus Sep 24 2001 A Cellular Glass Menagerie,
        Scientifc American web News in Brief 2001 Experiments Reveal How Cells Can Act Like Molten Glass
        Nature physics portal highlight 2001 Physics in biology: soft cells
        Boston Globe Oct 02 2001 Health/Science Briefs Cells like glass

16.    C. Que, C.M. Kenyon, R. Olivinstein, P.T. Macklem, G.N. Maksym. Homeokinesis and short-term variability of human airway calibre. J. Appl. Physiol. 91:1131-1141, 2001.

17.    M. P. Morales, M. Grabulosa, J.Alcaraz, J. Mullol, G.N. Maksym. J.J. Fredberg, D. Navajas. Demodulation algorithm to expand the frequency range of cell microrheology measurements by magnetic twisting cytometry. J. Appl. Physiol. 91:1152-1159, 2001.

18.    B. Fabry, G.N. Maksym, S.A. Shore, P.E. Moore, R.A. Panettieri, Jr., J.P. Butler, J.J. Fredberg. Time course and heterogeneity of responses to contractile and relaxing agonists in human airway smooth muscle cells in culture. J. Appl. Physiol. 91:986-994, 2001.

19.    G.N. Maksym, B. Fabry, J.P. Butler, D. Navajas, D. J. Tschumperlin, J.D. Laporte, J.J. Fredberg. Mechanical properties of cultured human airway smooth muscle cells from 0.05 to 0.4 Hz. J. Appl. Physiol. 89:1619-1632, 2000.
    (featured in an invited editorial: Hubmayr, R. Biology lessons from oscillatory cell mechanics, J. Appl. Physiol. 89:1617-1618, 2000)

20.    Fabry B, Maksym GN, Hubmayr RD, Butler JP, Fredberg JJ. Implications of heterogeneous bead behavior on cell mechanical properties measured with magnetic twisting cytometry. Journal of Magnetism and Magnetic Materials 1999; 194 :120-125
PDF (250 KB)

21.    Laporte JD, Moore PE, Abraham JH, Maksym GN, Fabry B, Reynold A. Panettieri RA, Shore SA. Role of ERK MAP kinases in responses of cultured human airway smooth muscle cells to IL-1 beta. Am J Physiol 1999 277:L943-L951
PDF (249 KB)

22.    Wang N, Butler JP, Ingber DE. Mechanotransduction across the cell surface and through the cytoskeleton
Science 1993; 260 :1124-1127, HTML-file

23.    G.N. Maksym, J.J. Fredberg and J.H.T. Bates. Force heterogeneity in a two-dimensional network model of lung tissue J. Appl. Physiol. 85: 1223-1229, 1998.

24.    G.N. Maksym, R.E. Kearney and J.H.T. Bates. Nonparametric block-structured modeling of lung tissue strip mechanics. Ann. Biomed. Eng. 26:242-252, 1997.

25.    G.N. Maksym and J.H.T. Bates. A distributed nonlinear model of lung tissue elasticity. J. Appl. Physiol. 82: 32-41, 1997.

list updated: 13 April 2007