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Dalhousie
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Course Descriptions

Approved Classes for 2010-2011
updated 8/26/2010

(A) = Fall Term; (B) = Winter Term

N.B. Where permissible in their degree programs--and subject to space availability--undergraduate students may enroll in SBME graduate courses. Undergraduate students must satisfy the following criteria: (i) Completion of first three years of a B.Eng. or B.Sc. program; (ii) Minimum B+ cummulative average; (iii) Permission of the instructor.

A Term classes (Fall):

BMNG 5050.03 (A&B) Introduction to Biomedical Technologies in Clinical Settings (Bance and Staff)
As of 2011/2012 this course is offered to non-CREATE students on a not-for-credit basis only

This class is part of NSERC CREATE BioMedic: A Training program in Biomedical Biomedical Technology Innovation and Commercialization. It focuses specifically on clinical exposure and apppreciation of the challenges of device development for clinical use. Areas of exposure are in clinical ethics, prinicples of human physiology and pathophysiology, biomedical device certification, technology challenges in challenging environments such as the operating room and clinic and sterilization issues. Students will be directly exposed to clinical procedures and procedures during the course.

This is a 2-term course having course components in both the Fall and Winter terms.

- More information on the NSERC CREATE BioMedic pages

BMNG 5110.03 (A) Biocompatibility and Biomaterials Design (Sarah Wells and Daniel Boyd)

Lectures: TBD
Location: TBD

This course deals with the scientific basis of biocompatibility (host and materials responses in biomaterials) and its application to intelligent design of biomaterials for implantable systems. The course will be divided into thirds: (i) cellular, tissue-level, and systemic responses to implanted devices, including thrombosis, wound-healing, cytotoxicity, and immunological responses; (ii) materials degradation including corrosion, dissolution, swelling/leaching, surface chemistry, etc.; (iii) case studies of materials and device design including: heart valves, total hip prostheses, dental restorative materials, total artificial heart, burn dressings and hemodialysis systems. The course text is "Biological Performance of Materials (3rd. Ed.) by Jonathan Black.

BMNG 5210.03 (A) Biomedical Instrumentation, Data Acquisition and Analysis (Adamson)

Lectures: Wednesday 10am to 11:30am, Thursday 10am to 11:30 am
Lab: Thursday 1-4 pm
Location: Dentistry, room 2006

This hands-on course is an introduction to computer-based data acquisition and analysis of physiological signals relevant to Biomedical Engineering. In an integrated series of lectures and laboratory projects, students will use A/D, D/A, and remote acquisition techniques to acquire real and simulated data from a variety of sensors (e.g. electrocardiograms, muscle activity, pressure, temperature, and sound). Issues such as sampling, aliasing, filtration, data storage, frequency domain analysis, error analysis and parametric model fitting will be examined. The course also provides a step-by-step introduction to programming with Scientific Python and Labview.
See course website here.

BMNG 5260.03 (A) Diagnostic Imaging and Radiation Biology (Brown)

Lectures: Monday 3:30-5:00pm, Wednesday 2:30-4pm
Location: Dentistry, room 5158

This course will discuss the basic principles behind modern medical imaging modalities including the mathematical foundations of image processing and image reconstruction from projections. The specific imaging modalities that the course covers are X-ray, CT, PET, MRI, and Ultrasound imaging. Fundmentals of ionizing radiation along with the interaction of radiation with tissue is also described. Students will all be required to perform one Magnetic Resonance Imaging lab/report using a bench-top Earth field MRI system.

BMNG 5310 (A) Business of Medical Technology I (David Roach, Faculty of Management)

Lectures: Tuesday 8:30-11:30am

Students will work in interdisciplinary teams to trial-develop a biomedical concept from idea to commercial product in this course and in the following course BMNG5311. Topics covered include: innovation and design Methodology and industry practice, industrial design and creativity in design, intellectual property fundamentals and industry practices, medical technology development processes. Teams combine students from biomedical engineering, medical residents and MBA programs.
- More information on the NSERC CREATE BioMedic pages

BMNG 5410.03, 5420.03, 5430.03 (A/B or summer term) Directed Readings in Biomedical Engineering (Staff)

This class is designed for students wishing to gain knowledge in a specific area in which no graduate level classes are offered. Class format is variable and may include seminars, lectures, and the study of papers and/or book chapters as part of a directed research or design project. Students are required to present the work (not less than 90 hours per semester), in a written report which will be evaluated. Normally a student can take only one directed reading class as part of their degree program.

B-Term Classes (Winter):

BMNG 5010.03 (B) Introductory Physiology for Biomedical Engineering (French)

The physiology of human organ systems including neurophysiology, cardiovascular, respiratory, renal, gastrointestinal and endocrine physiology.
For further information, see the Course Description.

BMNG 5120.03 (B) Biomechanics in Physiology and Surgical Implant Design (Veres)

This course deals with: (1) solid and fluid mechanical analysis of biological tissues and organs, and (2) use of mechanical engineering techniques in the design of implantable medical devices, e.g. heart valves, vascular grafts, ligament replacements, total artificial heart, and total hip or knee replacements. Topics to be covered include cell structure and mechano-electrical function, blood flow, arterial mechanics, bone structure and mechanics, mechanics and tribology of artificial joints, muscle mechanics, pulmonary function, fundamentals of gait and mobility aids. Guest lecturers from clinical sciences will help to develop the practical context of biomechanical engineering problems.
Exclusions: MECH 4650.03

BMNG 5140.03 (B) Principles of Biomolecular and Drug Molecule Design (Weaver)

An introductory course in biomolecular design, drug design and medicinal chemistry. Students are taught how to identify and formulate the design problem and they are provided with the conceptual and factual tools necessary to tackle the design problem and to design a new chemical entity as a putative therapeutic.
Cross Listing with CHEM 5601.03
Download course outline as PDF file.

BMNG 5150.03 (B) Introduction to Tissue Engineering (Gratzer).

Tissue engineering is a recent and fast-growing field which encompasses and unites biology, chemistry, medical sciences and engineering to design and fabricate systems to replace tissues and organs. Topics will include tissue engineering scaffolds, cell incorporation (selection and culture), in vivo versus in vitro constructs, and applications of tissue engineering.

BMNG 5230.03 (B) Biomedical Signal Analysis and Modeling (Maksym/French/Gonzalez-Cueto)

This course compliments BMNG5210 Biomedical Instrumentation Data Acquisition and Analysis. Analyzing physiological signals using quantitative engineering signal analysis techniques is a significant and important part of biomedical engineering. This course is directed at students interested in the analysis of physiological signals and modeling of physiological systems using mathematical methods. It is ideally paired with Biomedical Instrumentation which in the spring term covers data acquisition and transducer instrumentation through programming in Labview. In this course the focus will be on analysis of physiological signals using signal analysis approaches. The course is organized in a series of modules beginning with 3 core modules: Linear systems analysis, modelling and identification, and concluding with 5 optional modules from which the students together choose 2 or 3 including: orthogonal decomposition, biological statistical analysis and modeling, nonlinear system modeling, time-frequency analysis and time-series analysis of chaotic signals. Examples and assignments using physiological signals and models accompany each module. Assignments (60%) make use of matlab analysis and modelling methods and the final project is the analysis of real data or development of a model using techniques covered in class or researched by the student.
Download course outline as PDF file.

BMNG5320 (B) Business of Medical Technology II 
(David Roach, Faculty of Management + staff)

Students will work in interdisciplinary teams to trial-develop a biomedical concept from idea to commercial product in this course and in the following course BMNG5311. Topics covered include: innovation and design Methodology and industry practice, industrial design and creativity in design, intellectual property fundamentals and industry practices, medical technology development processes. Teams combine students from biomedical engineering, medical residents and MBA programs.
- More information on the NSERC CREATE BioMedic pages

BMNG 5410.03, 5420.03, 5430.03 (A/B or summer term) Directed Readings in Biomedical Engineering (Staff)

This class is designed for students wishing to gain knowledge in a specific area in which no graduate level classes are offered. Class format is variable and may include seminars, lectures, and the study of papers and/or book chapters as part of a directed research or design project. Students are required to present the work (not less than 90 hours per semester), in a written report which will be evaluated. Normally a student can take only one directed reading class as part of their degree program.

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Distance Courses: 

EE6913 (B) Advanced Biomedical Instrumentation,
University of New Brunswick Blackboard Learning System with no face to face lectures.

- This distance learning course offered by one of Adjunct Faculty at UNB may be of interest to some students:

This course deals with the problems and solutions encountered when applying biomedical instrumentation techniques to human subjects. The emphasis throughout the course is on the use of surface electrodes, however many of the concepts apply to other areas of instrumentation. The material is divided into six modules: 1 The origins of biopotentials 2 Biopotential electrodes 3 Differential amplifier design 4 Coupling with the environment 5 Patient isolation techniques 6 Low noise instrumentation Throughout the course the conflict between designing for best electrical performance and ensuring patient safety is highlighted. It is expected that prospective students have a working understanding of basic electrical engineering principles and have successfully completed an undergraduate program that includes electronics. This course is given through the Blackboard course delivery system and there are no scheduled face-to-face lectures.
http://www.ece.unb.ca/grad_courses.html#ee6913


Courses not offered this Fall/Winter:

BMNG 5020.03 (A) Cell Biology for Biomedical Engineering
This course is not being offered in 2011/12
This course provides an introduction to eukaryotic cell structure and function for engineering and physical science students who do not have a strong biological background. Topics include: cell structure, organelles, DNA, RNA, transcription and translation, protein production and processing, secretion, cytoskeleton, molecular motors, extracellular matrix, membrane transport, cell-cell communication, and cell division. Some emphasis will be placed on excitable cells, synaptic communication and muscle contraction.
For further information, see the Course Outline.

BMNG 5160.03 (B) Bioengineering in Orthopaedics and Dentistry (Filiaggi)
This course is not being offered in 2012
Orthopaedics and dentistry dominate the medical device market, providing some conspicuous examples of successful biomaterials engineering. This course will explore a number of biological and engineering considerations that arise in the design and development of implants for skeletal tissue replacement or regeneration, with an emphasis on bone / implant interactions.

BMNG 5040.03 (A) Introduction to Biomedical Engineering (Wells and Staff)

This course is not offered in 2011/12.
Biomedical Engineering includes both: design of devices, instrumentation, or processes for clinical use, and (ii) the application of engineering science and technology to the solution of problems in biological systems. This course will explore both these avenues with an emphasis on the distinctions between scientific and engineering approaches to research and development. Topics will include: the history of biomedical engineering, problem solving in the real world, defining design objectives, problem formulation and specification, experimental design and instrumentation, approaches to equipment design, statistical principles for measurement and quality control, optimization principles, economic considerations and impact of technology on medicine, safety and regulatory concerns, ethical concerns in animal and human experimentation, and grant application writing. Wherever possible, actual case studies will be used as examples wherein the above principles have (or have not) been successfully applied.
For further information see the Course Outline and Lecture Schedule

BMNG 5030.03 (B) Pathobiology for Biomedical Engineering
This course is not offered in 2011/12. A similar course is offered by pathology, please see PATH5000.

This course deals with the basic functional anatomical aspects of the human body, including research using animal models. The basic pathology of general mechanisms of disease, such as ischaemia, trauma, thermal lesions, infection, metabolic disease, degenerative disease (especially atherosclerosis, diabetes and degenerative joint disease) will be included at all times. The issues concerning malignant disease, both resulting from the primary condition as well as those developing from modern intensive therapy forms (inclusive of radiology etc.), will be presented in an integrated form with surgical interventions related to cancer surgery.

BMNG 5130.03 (B) Biomechanics of Human Gait (Astephen)
This course is not being offered in 2011/2012

An overview of the research in biomechanics of human motion with particular focus on gait analysis. Topics include measuring and analysis techniques, biomechanical modelling, and data analysis techniques. Applications include the study of normal, able-bodied gait, and the evaluation of gait pattern changes associated with osteoarthritis, total knee replacement, and stroke.

BMNG 5220.03 (B) Mathematical Analysis of Dynamic Biological Systems
This course is not offered in 2011/12

This course is concerned with the construction, analysis and interpretation of mathematical models of dynamical biological systems. Topics covered will include neural networks, electro-biology, epidemiology and the transmission of HIV, the morphology of complex biological and chemical systems and pattern formation in morphogenesis.

BMNG 5250.03 (B) Bioelectricity: A Quantitative Approach (Horacek)
This course is not offered in 2011/12

An introductory electrophysiology course, following a quantitative approach based on the general principles established in physics and engineering. The core material covers nonlinear membrane properties of excitable cells that produce action potentials, propagation of action potentials in one-, two- and three-dimensional excitable media, the response of excitable media to artificial stimuli, and the electromagnetic field that the active bioelectric sources produce in the surrounding extracellular space. Applications to the study of neural and cardiac electrophysiology will be discussed in detail.


 
   
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